UZAYAN KOVİD NEDİR, KİMLERDE GÖRÜLÜR, BELİRTİLERİ NELERDİR

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Çağla ile Yeni Bir Gün programında KOVİD’ in klinik tablolarını ve yeni tarif edilen “Uzayan KOVİD” i konuştuk.

Seyretmek için tıklayın:

https://www.youtube.com/watch?v=A-QaJbIr9Fs K: 

https://www.facebook.com/yenibirgunfox/

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EK 3 (7.12.2021): “Uzayan Kovid’ den mustarip olduklarını iddia eden 27 bin katılımcı üzerinde yapılan Fransız araştırmasında, sadece yüzde 4’ünün önceden virüsle karşılaştığı tespit edildi. Kaynak: https://twitter.com/korcanayata/status/1467938493376643075?s=20

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EK 4 (31.5.2022): Kapsamlı değerlendirmelerde, çoğu vakada belirtilerin sebepleri ortaya konamadı. Anormal sistemik immün aktivasyon veya kalıcı viral enfeksiyona ait delil bulunamadı. Antikor seviyeleri çok değişkendi.  Uzayan Kovid’ in patogenezi belli değildir.

Kaynak: https://www.acpjournals.org/doi/10.7326/M21-4905

Makale adı: A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings

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EK 5 (4.8.2022): Long COVID Comes in Three Forms: Study

Scientists have found three types of long COVID, which have their own symptoms and seem to appear across several coronavirus variants, according to a new preprint study published on MedRxiv that hasn’t yet been peer-reviewed.

Long COVID has been hard to define due to its large number of symptoms, but researchers at King’s College London have identified three distinct profiles — with long-term symptoms focused on neurological, respiratory, or physical conditions. So far, they also found patterns among people infected with the original coronavirus strain, the Alpha variant, and the Delta variant.

“These data show clearly that post-COVID syndrome is not just one condition but appears to have several subtypes,” Claire Steves, PhD, one of the study authors and a senior clinical lecturer in King’s College London’s School of Life Course & Population Sciences, said in a statement.

“Understanding the root causes of these subtypes may help in finding treatment strategies,” she said. “Moreover, these data emphasize the need for long-COVID services to incorporate a personalized approach sensitive to the issues of each individual.”

The research team analyzed ZOE COVID app data for 1,459 people who have had symptoms for more than 84 days, or 12 weeks, according to their definition of long COVID or post-COVID syndrome.

They found that the largest group had a cluster of symptoms in the nervous system, such as fatigue, brain fog, and headaches. It was the most common subtype among the Alpha variant, which was dominant in winter 2020-2021, and the Delta variant, which was dominant in 2021.

The second group had respiratory symptoms, such as chest pain and severe shortness of breath, which could suggest lung damage, the researchers wrote. It was the largest cluster for the original coronavirus strain in spring 2020, when people were unvaccinated.

The third group included people who reported a diverse range of physical symptoms, including heart palpitations, muscle aches and pain, and changes to their skin and hair. This group had some of the “most severe and debilitating multi-organ symptoms,” the researchers wrote.

The researchers found that the subtypes were similar in vaccinated and unvaccinated people based on the variants investigated so far. But the data showed that the risk of long COVID was reduced by vaccination.

In addition, although the three subtypes were present in all the variants, other symptom clusters had subtle differences among the variants, such as symptoms in the stomach and intestines. The differences could be due to other things that changed during the pandemic, such as the time of year, social behaviors, and treatments, the researchers said.

“Machine learning approaches, such as clustering analysis, have made it possible to start exploring and identifying different profiles of post-COVID syndrome,” Marc Modat, PhD, who led the analysis and is a senior lecturer at King’s College London’s School of Biomedical Engineering & Imaging Sciences, said in the statement.

“This opens new avenues of research to better understand COVID-19 and to motivate clinical research that might mitigate the long-term effects of the disease,” he said.

Kaynak: https://www.medscape.com/viewarticle/978469?src=soc_tw_220803_mscpedt_news_mdscp_longcovid&faf=1

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EK 6 (13.8.2022): BROWNSTONE INSTİTUTE “Mikroplastiklere, nanopartiküllere, maskelerdeki kimyasallara ve nazofaringeal testleredaha çok maruz kalma, Uzayan Kovid’ i tanımlayan semptomların çoğuna paraleldir.”

Resim

Kaynak: https://twitter.com/brownstoneinst/status/1558031118661722113

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EK 7 (25.8.2022): Uzayan Kovid diğer post-viral durumlara benziyor. Kaynak: https://www.medscape.com/viewarticle/979690 Makale: Long COVID Mimics Other Post-Viral Conditions

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EK 8 (3.12.2022): Association of Initial SARS-CoV-2 Test Positivity With Patient-Reported Well-being 3 Months After a Symptomatic Illness

 In this study, participants in both the COVID-19–positive and COVID-19–negative groups reported persistently poor physical, mental, or social well-being at 3-month follow-up. Although some individuals had clinically meaningful improvements over time, many reported moderate to severe impairments in well-being 3 months later. These results highlight the importance of including a control group of participants with negative COVID-19 results for comparison when examining the sequelae of COVID-19.

Kaynak: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2799116

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    Bu yazıdaki resim herhalde eski olmalı çünkü videodaki gömlek kravat farklı. Bizden kaçmaz hocam?

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